Down-regulation of HANR enhanced chemosensitivity to doxorubicin in HCC cell lines [91], NR2F1-AS1 regulated HCC oxaliplatin resistance by targeting miR-363-ABCC1 pathway [92], and knockdown of lncRNA HOTAIR sensitized HCC cells to cisplatin through regulating the STAT3/ABCB1 signaling pathway [93]. This evidence concerns the gene ABCB1 and hepatocellular carcinoma.