Similarly, infection of cells with the human rotavirus Wa strain, which uses a clathrin-, cholesterol-, and dynamin-dependent entry process [51, 52], was significantly inhibited by chlorpromazine, MβCD, and dynasore (Figure 1), by siRNA depletion of clathrin or dynamin (Figure 2), as well as by DN mutants of the clathrin adaptor protein Eps15 and dynamin II (Figure 3). The gene discussed is DNM2; the disease is infection.