According to the WHO the pNETs were graded as NET G1 (n = 32 (56.1%)), NET G2 (n = 17 (29.8%)), and NEC (neuroendocrine carcinoma) G3 (n = 8 (14.0%)) with a mean Ki-67 associated proliferative and H&E/pHH3-associated mitotic activity of 10.8% and 12.8/15.0 per 10 high power fields. The gene discussed is MKI67; the disease is neuroendocrine carcinoma.