MPN patient samples were characterized by the presence of JAK2 (c.1849G>T p.V617F), KIT (c.1655T>C p.M552T) and MPL mutations (MPL:c.1544G>T p.W515L and MPL:c.1841G>A p.G614E). The gene discussed is JAK2; the disease is myeloproliferative neoplasm.