G6PD and thalassemia: The best characterized of these polymorphisms are common disorders of hemoglobin, with single amino acid substitutions in β-globin (hemoglobin S, C, and E) or reduced production of α- (α-thalassemia) or β- (β-thalassemia) globin [3], and deficiency in glucose-6-phosphate dehydrogenase (G6PD), which protects erythrocytes from oxidative stress[1].