PROM1 and colorectal carcinoma: Although proper outcome assessment of pMMR and CD133-positive tumors would require larger study populations and longer follow-up, which was not included as part of this study, expression of CD133 (Bin et al., 2014; Kashihara et al., 2014) and proficient MMR or MSS (microsatellite stability) (Lin et al., 2014; Seppala et al., 2015) in CRC are generally associated with poorer outcomes.