EGFR and non-small cell lung carcinoma: Consistent with earlier reports [15, 16, 17], treatment with 10 μM gefitinib, which efficiently inhibited the growth of NSCLC cells with activating mutations (PC-9 and HCC827, Figure 2A and 2B), only modestly or marginally inhibited the growth in NSCLC cells with wt-EGFR (A549 and H1299, Figure 2C and 2D).