Prompted by the observation that GLUT1 expression and glucose uptake are increased in gefitinib-resistant NSCLC cells, we next examined the impact of GLUT1 inhibition on the sensitivity/resistance of NSCLC cells to gefitinib by use of WZB-117, a pharmacological inhibitor of GLUT1 [13, 14]. The gene discussed is SLC2A1; the disease is non-small cell lung carcinoma.