BRCA2 and Fanconi anemia: Thus, while these arrested forks in the fission yeast were dysfunctional, the ssDNA associated with unprotected, but otherwise functional, forks in human cells could cause a similar failure of fork merging: RAD51, BRCA2 and the Fanconi anaemia pathways may hence function to maintain transiently arrested forks in a conformation that is competent for termination.