IGHE and Increased total eosinophil count: This results from sustained exposure to aeroallergens, including house dust mite (HDM) and fungal spores, which lead to elevated concentrations of type 2 cytokines IL‐4, IL‐5 and IL‐13, alongside allergen‐specific immunoglobulin E (IgE), eosinophilia and airway hyper‐responsiveness (AHR),1.