However, similar to GS, AQP4 expression varied in different experimental models of epilepsy (Eid et al. 2005; Lee et al. 2004; Lee et al. 2012), ischemic/anoxic insult (Aoki et al. 2003; Hoshi et al. 2011), or hepatic encephalopathy (Rama Rao et al. 2010; Wright et al. 2010; for reviews, see Badaut et al. 2014; Saadoun and Papadopoulos 2010; Potokar et al. 2016). The gene discussed is AQP4; the disease is epilepsy.