IGF2BP1 and osteosarcoma: On the basis of our data, altered levels of miR-150 and IGF2BP1, alone or in combination, were all significantly associated with advanced clinicopathological features and short survival of patients with osteosarcomas, implying that the imbalance of miR-150-IGF2BP1 axis may lead to aggressive progression and poor prognosis of this malignancy.