The median values of miR-150 (2.56) and IGF2BP1 protein IRS (5.62) in all 100 osteosarcoma tissues were respectively used as cutoff points to classify the patients with osteosarcomas into miR-150-low (n = 52, 52.00%), miR-150-high (n = 48, 48.00%), IGF2BP1-low (n = 49, 49.00%) and IGF2BP1-high (n = 51, 51.00%) expression groups. This evidence concerns the gene IARS1 and osteosarcoma.