LDHA and cancer: In addition, although ALDH1A1 has long been regarded as a marker for poor prognosis in several cancer types and the ALDEFLUOR assay defined ALDH+ portion has long been owed to ALDH1A1, several groups have analyzed the expression of ALDH isoforms in proteomic data (Zhang et al. 2011) or transcriptomic data (Chang et al. 2018) of several cancer types and unraveled that some other ALDH isoforms are either positively or negatively correlated to prognosis.