Based on the phenomenon that anaplastic lymphoma kinase (ALK) mutation (F1174C) promoted growth and upregulated the expression of neuroendocrine marker neuron-specific enolase in the organoids of prostate small cell carcinoma, alectinic showed more significant effects than crizotinibin terms of inhibiting ALKF1174C-expressing cell expansion [117]. Here, ALK is linked to prostate small cell carcinoma.