Also, by comparison to patients with Hu‐ or Ma2‐antibody‐associated encephalitis, patients with GAD65‐antibody encephalitis showed lower CD8/CD3 ratios, indicating an appropriate designation of GAD65 antibodies between other intracellular autoantibodies and NSAbs.62 These collective observations lead to the intriguing notion that GAD65 antibodies may have some causative potential. This evidence concerns the gene CD8A and encephalitis.