TGFB1 and hypertrophic cardiomyopathy: As shown in Fig. 3C, and Supplementary Table S3, all the T3DE-miRNAs were predicted to have a role in the selected processes leading to adverse remodeling (“apoptosis”, “p53 signaling”, “Tgfb signaling” and “ECM receptor pathways”), and heart disease evolution (“hypertrophic cardiomyopathy” and “dilated cardiomyopathy”).