TIPE3 and nasopharyngeal carcinoma: To verify whether the TIPE3 CGI was hypermethylated in NPC, we further tested the methylation levels of cg05905176 (the most significantly hypermethylated CpG site ranked by p value) in another eight NPC tissues and eight NPEC tissues, as well as five NPC cell lines and three NPEC cell lines using bisulfite pyrosequencing.