As shown in Table 3, four factors, including depth of invasion (hazard rate (HR) = 1.883; 95% CI 1.135–3.122; P = 0.014), TNM stage (HR = 2.349; 95% CI 1.342–4.114; P = 0.003), XRCC5 expression (HR = 1.795; 95% CI 1.076–2.994; P = 0.025), and CLC-3 expression (HR = 1.671; 95% CI 1.012–2.758; P = 0.045), were associated with the clinical outcomes of GC patients. Here, XRCC5 is linked to gastric cancer.