HLA-DRB1 and rheumatoid arthritis: Alsaied et al. [42] found an association between HLA-DRB1*03 and juvenile RA in Kuwaiti Arab children, and Manivel et al. [43] established an association between HLA-DRB1*03 and RA subtype anti-CII (anti fibrillar collagen type II) in the Swedish population.