A recent study by Tang et al. illuminated its influence on the process of EMT in PDAC by post-transcriptional regulation of the EMT-regulators SNAIL1 and Notch1 [17] while Ahn et al. reveal microRNA-34a as a target of ZEB-1 and showed its tumor-suppressive functions by decreasing tumor cell invasion and metastasis [18]. This evidence concerns the gene NOTCH1 and neoplasm.