The combination of PD-L1 expression ≥1% tumor cells with a CD8+ density lower than the median (p = 0.002; HR, 4.2; 95% CI, 1.5–12), or with a CD33+ density lower than the median (p = 0.007; HR, 4.7; 95% CI, 1.7–13) identified a subset of LADC patients with poor OS (Figure 3, Table S2). Here, CD8A is linked to neoplasm.