Albertson et al. proved that the amplification of the CYP24A1 gene in human breast tumors and analysis of the datasets from The Cancer Genome Atlas confirms that a subset of human breast cancers (10–13%) exhibit alterations in the CYP24 gene, with the most frequent changes being amplifications and up-regulation at the mRNA level [32]. The gene discussed is CYP24A1; the disease is breast carcinoma.