Additionally, NRPs have been implicated in mediating EMT in other cancer types.95, 96 Recently, it was discovered that the EMT program is dispensable for metastasis, but induces chemoresistance in pancreatic cancer.97 Therefore, examining the role of NRP‐1 in EMT and associated chemoresistance in PDAC requires prompt attention. This evidence concerns the gene NRP1 and familial pancreatic carcinoma.