KAT2B and hepatocellular carcinoma: In addition, its overexpression induces HCC cell apoptosis and autophagy.119 PCAF has also been proposed to act as a metastasis suppressor of HCC by restraining the activity of transcription factor glioma‐associated oncogene homologue‐1 (Gli1), thus inhibiting the epithelial‐to‐mesenchymal transition (EMT) of HCC cells.120 EMT is controlled by a group of transcriptional repressors, including Gli1.