The P300/CBP‐associating factor (PCAF) is a histone acetyltransferase (HAT) that primarily acetylates H3 histones and has a strong association with tumour initiation and progression, and it is similar to other HAT family member‐GCN5 eukaryotes.36 Using various nutritional, genetic, and pharmacological model systems, the roster of PCAF‐acetylated lysine sites has rapidly expanded. Here, KAT2B is linked to neoplasm.