Hyperlipidaemia is a prevalent disease and a major component of metabolic syndromes.45, 46 In a physiological study, using a diabetic pregnant rat model, Abraham and colleagues showed that increased hepatic de novo lipogenesis directly contributes to hyperglycaemia and hyperlipidaemia.47 Apolipoprotein apoC‐III is important in lipogenesis and triglyceride (TG) metabolism. This evidence concerns the gene APOC3 and hyperlipidemia.