It is still challenging to detect pTa bladder cancer (SLC2A1, AUC 0.64 (95% CI 0.55 – 0.74)) since 87% of the pTa samples were lower grades (G1/G2) although those cancers have a low risk for recurrence, while high-risk pTa/G3 bladder cancer may be detected with better diagnostic performance (SLC2A1, AUC 0.76 (95% CI 0.62 – 0.91)). This evidence concerns the gene SLC2A1 and urinary bladder cancer.