For the detection of non-bladder urothelial cancer (RPC and URC, N=32), KRT17 showed the best diagnostic performance with AUC 0.77 compared to 0.51 to 0.64 for urine cytology and BTA assays (Supplementary Figure 2, Supplementary Table 6). The gene discussed is KRT17; the disease is bladder transitional cell carcinoma.