TSLP and neoplasm: To determine whether the tumor microenvironment affects circulating levels of TSLP, basal plasma TSLP concentrations were measured in patients with locally-advanced or metastatic PDAC, and compared with those of normal subjects; the former were higher than the latter [median (range): 5.74 (0–152.9) pg/ml vs. 4.65 (0–9.6) pg/ml, p = 0.040] (Figure 5).