Leucine-rich α2 glycoprotein (LRG1) has been identified as a marker of granulocyte differentiation, is involved in neovascularization by altering TGFα signaling at endothelial cells (Wang et al., 2013), and has recently been found elevated in plasma associated with distinct cancers including pancreatic (Capello et al., 2017). The gene discussed is TGFA; the disease is cancer.