High levels of GPR56 expression were detected in two AML samples with either inv(3) (P1) or t(3;21) (P2), and low levels of GPR56 expression were detected in two AML samples (P3 and P4), as determined by real-time RT-PCR and FCM analysis using a PE-labeled anti-GPR56 antibody (Supplementary Fig. S4a–c). Here, ADGRG1 is linked to acute myeloid leukemia.