Concomitant with the increase in PPARγ2 expression, overexpressing JMJD2B stimulated the expression of hepatosteatosis genes including fatty acid uptake-associated genes CD36, FABP4 (Fig. 2D) and lipid droplet-associated genes PLIN2, CIDEC (Fig. 2E) in HepG2 cells, which are known PPARγ2 steatosis target genes. The gene discussed is PLIN2; the disease is steatosis.