IL33 and Hepatitis: Since ST2+ Tregs have been described as an activated Treg subset with potent immunosuppressive function in inflammation [145,146,147], it could be speculated that absence of ST2+ Tregs in ST2-deficient mice and defective activation of this Tregs subset in IL-33-deficient mice might be responsible for the observed aggravated liver injury in ConA-induced hepatitis (Figure 3).