On the one hand, IL-33 drives immunity by promoting type 2 or type 1 immune responses, eosinophilia, ILC2 activation, M2 macrophage polarization, and epithelial cell damage whereas on the other hand, IL-33 suppresses inflammation by expansion of Tregs and activation of myeloid-derived suppressor cells. This evidence concerns the gene IL33 and Increased total eosinophil count.