It has been known that not all hepatoid gastric adenocarcinoma produce AFP, some patients express negative.[1] Although hepatoid adenocarcinoma is the most common, there are some other types of AFP-producing gastric cancer, such as yolk sac tumor-like and fetal gastrointestinal type.[1,9] And in some AFP producing cases, the component of the tumor is not unique.[10] According to the literature, the incidence of AFP producing gastric cancer is 1.3% to 15%.[10] Above all, there is some clinical experience. The gene discussed is AFP; the disease is gastric cancer.