On assessing the data, a significant association was found between high Her3 expression and tumor differentiation (OR = 2.38; 95% CI: 1.76–3.22; P < .001; Fig. 2A), tumor stage (OR = 0.71; 95% CI: 0.53–0.96; P = .03; Fig. 2B), and position of colon cancer (OR = 1.71; 95% CI: 1.28–2.27; P < .001; Fig. 2C). Here, ERBB3 is linked to colonic neoplasm.