CD40LG and rubella: Among these 76 patients, 72 (34.8% of 207 with suspected CRS, all of whom met clinical criteria) were classified as laboratory-confirmed CRS, and four were categorized as having congenital rubella infection (positive rubella IgM in the absence of cataracts, congenital glaucoma, pigmentary retinopathy, congenital heart defects, or hearing loss (Box).