According to the univariate analysis, older age (P<0.001), larger SV diameter (P<0.001), female gender (P=0.003), a history of stroke (P=0.012), TKA surgery type (P<0.001), RBC count (P=0.001), and Hb levels (P=0.002) were significantly correlated with postoperative total DVT. The gene discussed is GSTM1; the disease is stroke disorder.