In short, whether in the prophylactic or colitis treatment period, the effect of Cp in acute colitis mice can be divided into two aspects: on the one hand, after orally administration of Cp to the intestine, Cp was degraded by thousands of carbohydrate-enzymes encoded by the gut microbiome and was broken down into small molecules by the fermentation of intestinal microbes, which were then absorbed by the host to exert pharmacological activity. This evidence concerns the gene CP and colitis.