MSH2 and hereditary nonpolyposis colon cancer: Similarly, genetic testing for HNPCC requires the analysis of MLH1, MSH2, MSH6, PMS2, and EPCAM coding sequences, while the panel for diagnosis of colon polyposis would involve APC, MUTYH, NTHL1, POLE, POLD1, SMAD4, BMPR1A, STK11, and MSH3 (Weren et al., 2015; Adam et al., 2016; Bellido et al., 2016; Kanth et al., 2017).