In our previous work on wt and Pten−/−TP53−/− primary prostate cells (32) and murine PCa cell lines PLum (37), generated spheres were characterized through immunofluorescent staining, showing the expression of lineage markers of basal (CK5), luminal (CK8) and neuroendocrine cells (β3 tubulin) of prostate tissue. The gene discussed is KRT5; the disease is posterior cortical atrophy.