Similarly, Martínez-Larradet al. 22, in a combined analysis conducted in non-diabetic individuals from the Mexico City Diabetes Study, the San Antonio Heart Study and Spanish Insulin Resistance Study, observed that the TyG index had higher AUC (between 0.673-0.875) to discriminate ≥10% risk coronary in 10 years than the HOMA-IR (between 0.579-0,746), as well as other less used IR indices, such as the McAuleys index and the insulin sensitivity index of Avignon. The gene discussed is INS; the disease is Insulin resistance.