IFNB1 and myeloid sarcoma: The mechanism of these symptoms is due to the obstruction of small blood vessels which causes secondary organ damage due to ischemia.1 Moreover, studying the literature shows that TTP-HUS has been reported in association with many inflammatory diseases and treatment with certain drugs.2 Multiple sclerosis (MS) is a demyelinating disease of the central nervous system which is treated with several drugs including interferon beta.3 Interferon beta-1a and interferon beta-1b have induced TTP-HUS in cases of patients with MS worldwide.4