IGF1 and Hypoglycemia: In fact, at rest, the brain accounts for 60% of the total basal glucose consumption, with its limited glycogen reserves, so it is not surprising that some of the primary symptoms of hypoglycemia are neurologic.5 In our case, endocrinology tests were performed, revealing the low levels of serum insulin and C-peptide which did not suggested an exogenous or endogenous hypoglycemia, but an IGF-mediated one.