PRLR and pituitary gland adenoma: In the non-hormone expressed nonfunctional pituitary adenoma (NF-NFPA) group relative to controls (Table 3), hPRL was downregulated by 8.3-fold in spot v1 and 4.9-fold in spot v2, was not changed in spot v3, and was lost in spots v4, v5, and v6.