Moreover, the overall proportional ratio of six PRL variants was significantly different among the five subtypes of pituitary adenomas (NF−, FSH+-, LH+-, FSH+/LH+-, and PRL+-adenomas) analyzed here with the Chi-square test performed with SPSS 22 software (p < 0.05) (Figure 4). This evidence concerns the gene BRD2 and pituitary gland adenoma.