Although there is still a lack of studies evaluating BDNF concentrations following exercise in subjects post-stroke, evidence based on stroke-induced animal models suggests a relationship between aerobic exercise training and an increase in BDNF concentrations (14–16) Furthermore, recent studies have also measured BDNF concentrations following functional task training in stroke-induced animals models, such as skilled reach training, in order to further clarify the mechanisms by which these interventions would induce recovery (17, 18). This evidence concerns the gene BDNF and Stroke.