The MNT containing EGF as its ligand module and carrying 125I (labeled by N-succinimidyl-4-guanidinomethyl- 3-[125I]iodobenzoate) accumulated in the nuclei of human epidermoid carcinoma A431 cells very efficiently: 60% of the radioactivity entering the cells appeared in the nuclei (Slastnikova et al., 2012b). Here, EGF is linked to squamous cell carcinoma.