These effects were observed for 111In delivered by two types of MNTs: one, DTox-HMP-NLS-MSH, targeted at cancer cells overexpressing melanocortin receptors-1 (experiments on B16-F1 mouse melanoma cells) and another, DTox-HMP-NLS-EGF, targeted at EGFRs (EGFR; experiments on U87.wtEGFR human glioblastoma and A431 human epidermoid carcinoma cells) (Slastnikova et al., 2017a). This evidence concerns the gene EGF and cancer.