Normal development, morphology (24–48 hpf); normal larval locomotor activity (5–7 dpf)No difference in brain size (2 weeks old); increased apoptosis in brain (3 weeks old)Adult Phenotypes: Microcephaly; decreased anxiety, social behavior impairments, decreased c-fos, crh expression in hypothalamic regions after social interaction, social isolation, respectively. The gene discussed is FOS; the disease is Anxiety.