Association tests were nominally significant for 14 of 172 missense variants tested in the seven genes previously associated with AD in AAs including a common SNP in ABCA7 (rs5985184, p = 0.0043) and the rare missense variants in AKAP9, rs149979685 (OR = 10.73, p = 0.0046) and rs144662445 (OR = 6.35, p = 0.0054), previously identified in a sample that overlaps substantially with the discovery cohort in this study (Logue et al., 2014) (Table 3). Here, AKAP9 is linked to Alzheimer disease.