TJP1 and intestinal disorder: In conclusion, L. reuteri LR1, in a MLCK-dependent manner, offset the decreased content of TJ proteins ZO-1 and occludin in IPEC-1 cells, otherwise caused by the damaging effect of ETEC K88 infection, suggesting that L. reuteri LR1 might offer promise for treating intestinal disorders with impaired function of the epithelial barrier.