To that aim, a 21 gene PCR array was specifically designed to measure the expression of mucins, mitogen-activated protein kinases, Krüppel-like factors, cytokines, markers of oxidative stress, cell proliferation, apoptosis and inflammation, and proteins previously detected to be differentially expressed in AGD in a proteomic study31 (Table 1). This evidence concerns the gene WNK2 and argyrophilic grain disease.