AKT1 and metabolic dysfunction-associated steatotic liver disease: Changes in the LC3-II/LC3-I and p62/actin ratios were not significant, which might be due to the mild autophagy response; however, changes in the p-AKT/AKT, p-mTOR/mTOR and LC3-II/actin ratios were significant compared with those in the MCD group (Fig. 7A), which indicated that autophagy is accelerated by JZG in the NAFLD mouse model.