ATF6 and non-small cell lung carcinoma: β-Elemene upregulated endoplasmic reticulum stress-related proteins (ERs), such as protein kinase R-like endoplasmic reticulum kinase (PERK), inositol-requiring protein 1α (IRE1α), and activating transcription factor 6 (ATF6); meanwhile, β-elemene downregulated Bcl-2 expression, thereby inducing apoptosis in NSCLC cells.