The data showed that the mRNA level of LYAR increased in both PR8 H1N1 (Fig. 4A) and HM H5N1 (Fig. 4D) virus-infected cells, which is correlated with virus replication during the infection course (Fig. 4B and E), suggesting that IAV infection upregulates the expression of LYAR at the transcriptional level. Here, LYAR is linked to infection.