The CAR-T cells were also evaluated for IFN-γ production after co-culture with multiple myeloma cell lines; BCMA CAR-T cells produced IFN-γ in response to RPMI8226, H929, and MM1S cells, but not in response to BCMA-negative K562 control cells (Figure 3D). The gene discussed is IFNG; the disease is AL amyloidosis.